The C. elegans SYS-1 Protein Is a Bona Fide β-Catenin
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چکیده
منابع مشابه
The C. elegans SYS-1 protein is a bona fide beta-catenin.
C. elegans SYS-1 has key functional characteristics of a canonical beta-catenin, but no significant sequence similarity. Here, we report the SYS-1 crystal structure, both on its own and in a complex with POP-1, the C. elegans TCF homolog. The two structures possess signature features of canonical beta-catenin and the beta-catenin/TCF complex that could not be predicted by sequence. Most importa...
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ژورنال
عنوان ژورنال: Developmental Cell
سال: 2008
ISSN: 1534-5807
DOI: 10.1016/j.devcel.2008.02.015